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What is the effect of Fluoxymesterone(Halotestin) on men?
- Oct 26, 2020 -

Fluoxymesterone(Halotestin) is a synthetic derivative of test, specifically methyltestosterone derivative (test, which is methylated).Halotestin is not able to be aromatized to estrogen, and has a very strong androgenic activity.Anabolic power of Halotestin is rated number 1900 and androgenic strength rated with value 850. Having compared these values with testwe see how Halotestin has immense power in terms of its anabolic capacity to build muscle as well as its androgenic strength.


Halotestin has added methyl group at carbon 17 (hence the name derived from 17-alpha) and halo-group on the 9th carbon.Adding a methyl group at carbon 17 is the change that provides the hormone the ability to survive metabolism in the liver, and thus allow a greater amount of hormone to successfully get into the bloodstream. Unfortunately, this modification also increases the rate of hepatotoxicity (liver toxicity). Connecting halogen to any substance is called halogenation. In our case to the test was attached with fluorine (halogenated).


The halogenation is responsible for the massive increase in androgen and anabolic forces of halotestin oral compared with testosterone and methyltestosterone.Compared with test Halotestin has one more change and that is the attached hydroxyl group (an oxygen bonded to a hydrogen atom) on the 11th arbon.Connection of the hydroxyl group at carbon-11 accounts for the Halotestin inability to react with enzyme aromatase and therefore preventing it conversion to estrogen.

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