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Rongxin Bio-Tech Co.,Ltd(H.K.)

FAX: 029-62388781

FEL: +8618220537895

E-mail: [email protected]

Address: Xi'an Jianshe Mansion,China, Shaanxi Sheng, Xian Shi, Yanta Qu, QuJiang ShangQuan, Yanta S Rd

Exemestane(Aromasin)

Main product information:
Product Name: Exemestane(Aromasin)
Name:Boldenone Undecylenate
CAS: 107868-30-4
MF: C20H24O2
MW: 296.4
Mp: 155.13°C 〈br/〉 Assay :99%
Storage temp:Store at -20°C
Appearance:White Or Almost White Crystalline Powder
Packaging: Bubble/ aluminum foil bag/box
Arrive Time:4-7 days

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Product Details

Exemestane(Aromasin)

Product details


NameExemestane
Other nameAromasin
Content99%
MFC20H24O2
MW296.4
CAS107868-30-4
AppearanceWhite Or Almost White Crystalline Powder
Min order quantity10grams.
Quality standardEnterprise Standard
Shipping MethodEMS,DHL,UPS,TNT or FEDEX,HKEMS.
PackingAs your require
payment MethodBank Transfer Bitcion
StorageKeep it under seal in cool and dark place
CertificationGMP, ISO 9001, USP, BP
GradePharmaceutical Grade
PackageIn foil bag or drum
ManufactureRongXin
UsagePharmaceutical material, Steroid hormone, Anabolin. As a male hormone and anabolic hormones.
Product CategoriesBoldenone Base(1-Dehydrotestosterone),Steroids;Intermediates & Fine Chemicals;Pharmaceuticals;Steroid and Hormone;API

Exemestane(Aromasin) .jpg

Product description

Aromasin is also known as Exemestane, as it is most commonly called, is a very potent AI which works by blocking the aromatase enzyme in the body. This drug was originally developed to help fight breast cancer in women by reducing estrogen which some believe to aid in cancer cell growth. While not quite as strong as Letrozole, Exemestanes is considerably stronger than Anastrozole.

Aromasin is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Exemestanes is also used to help prevent the cancer from returning. Some breast cancers are made to grow faster by a natural hormone called estrogen. Exemestanes decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.It acts by blocking the enzyme aromatase, subsequently blocking the production of estrogen.It is usually not used in women of childbearing age.


Fuction of Exemestane

A) Exemestane for breast cancer prevention:

Chemoprevention of breast cancer is an effective strategy to reduce the incidence of this disease in women at risk. The first agents to show a significant chemopreventive effect were the SERMs tamoxifen and raloxifen. An updated comprehensive analysis of all SERM prevention trials showed that they are able to reduce the incidence of breast cancer in high- and average-risk women, an effect that is sustained by a reduction in ER-positive invasive breast cancer.

B) Exemestane is a third-generation irreversible steroidal inactivator of the aromatase enzyme and is effective in all the treatment settings for breast cancer, including chemoprevention.

In the metastatic setting, exemestane has been extensively investigated as the first-line, second-line, and further-line treatment and is now registered for the treatment of postmenopausal women with advanced hormone-receptor-positive breast cancer whose disease has progressed following antiestrogen therapy. Of note, the potential lack of cross-resistance with NSAIs yields additional opportunities in the treatment sequence of endocrine agents. Furthermore, based on clinically meaningful results, exemestane with everolimus represents an effective therapeutic option for a disease that has progressed after exposure to NSAIs.

Exemestane is generally well tolerated, with a side effect profile similar to that of other AIs and including menopausal symptoms, arthralgia, bone loss, and altered lipid metabolism.


Our test Specification


TEST ITEMS

SPECIFICATION

RESULTS

Description

White Crystalline Powder

White Powder

Identification

Positive

Positive

Assay(by HPLC)

98.0~102.0%

98.64%

Absorbance(E25px)

465~495

482.5

Melting Point

191~195°C

193.5~195.0°C

Loss On Drying

0.5%max

0.19%

Specific Rotation

+288°~ +298°

+290.2°

Residue On Ignition

0.1%max

0.03%

Related Substances

Total:1.5%max

<1.3%

Test

Single:0.5%max

<0.4%

Residue Solvents

0.2%max

0.10%

Heavy Metals

20PPm max

<10PPm

Conclusion

The specification conform with enterprise standard.




Rongxin Bio-Tech company’s Competitive Advantage to you

1. Quality: all products are produced under GMP, purity more than 99%.
2. More competitive price from factory directly.
3. Customized:accept,we would supply OEM service for the Peptides,hgh,steriods raw powders and other products.
4. Prompt delivery day :shipment will do within 3 working day after receive payment.
5. Safe shipping: bubble+aluminum bag+carton

6. Payment methods: Money gram, western union,T/T advance or bank transfer payment.



Contact information

Enterprise mailbox:[email protected]

Skype:[email protected]

Whatsapp:+86-18729210590



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